A/Prof. Dr.Christian Soeller(Deputy Director - Polymer Electronics Research Center)website
email: c.soeller@auckland.ac.nz
phone: +64 9 373 7599 ext 82770
Research Interests:
I am a principal investigator in the Biophysics and Biophotonics group within the department of physiology. My research focuses on the use of photonics to illuminate basic biomedical questions.

A key interest is the detailed biophysical mechanism of cardiac excitation-contraction coupling and its relationship to cardiac contractility. The approach is quantitative whenever possible and I use mathematical modelling as a way to formulate hypotheses in a fairly rigorous way to test if our observations are compatible with suggested mechanisms.

New insight in physiology (and biology in general) often results from the availability of new technologies to probe cell systems. A large thrust of my work is therefore directed at developing novel ways to visualize structure and function at ever increasing spatial and temporal resolution.

Recently I started a fruitful interdisciplinary collaboration with colleagues from chemistry and engineering that led to the creation of the Polymer Electronics Research Center (PERC) at the university. A major goal is to construct biosensors with increased sensitivity and selectivity from self-assembled nanostructures. A variety of electrical and photonics readout methodologies is used to allow interfacing with modern microelectronics.

Selected Publications

D. Baddeley, D. Crossman, S. Rossberger, J. E. Cheyne, J. M. Montgomery, I. D. Jayasinghe, C. Cremer, M. B. Cannell, C. Soeller4D Super-Resolution Microscopy with Conventional Fluorophores and Single Wavelength Excitation in Optically Thick Cells and TissuesPLoS ONE6 (5)e206452011paper
S. Carlson, J. Trial, C. Soeller and M. L. EntmanCardiac Mesenchymal Stem Cells Contribute to Scar Formation After Myocardial InfarctionCardiovascular Research91 (1)12011paper
H. Peng, L. Zhang, C. Soeller and J. Travas-SejdicConducting polymers for electrochemical DNA sensingBiomaterials30 (11)2132-21482009paper
J. B. Spires, H. Peng, D. E. Williams, B. E. Wright, C. Soeller and J. Travas-SejdicThe effect of the oxidation state of a terthiophene-conducting polymer and of the presence of a redox probe on its gene-sensing propertiesBiosensors and Bioelectronics24 (4)928-9332008paper
C. Soeller, D. Crossman, R. Gilbert, and
M. B. Cannell
Analysis of ryanodine receptor clusters in rat and human cardiac myocytesProceedings of the National Academy of Sciences104 (38)14958-149632007paper